One of the main challenges of Topological Data Analysis (TDA) is to extract features from persistent diagrams directly usable by machine learning algorithms. Indeed, persistence diagrams are intrinsically (multi-)sets of points in $\mathbb{R}^2$ and cannot be seen in a straightforward manner as vectors. In this article, we introduce $\texttt{Persformer}$, the first Transformer neural network architecture that accepts persistence diagrams as input. The $\texttt{Persformer}$ architecture significantly outperforms previous topological neural network architectures on classical synthetic and graph benchmark datasets. Moreover, it satisfies a universal approximation theorem. This allows us to introduce the first interpretability method for topological machine learning, which we explore in two examples.