Comprehensive Evaluation of Multimodal AI Models in Medical Imaging Diagnosis: From Data Augmentation to Preference-Based Comparison

This study introduces an evaluation framework for multimodal models in medical imaging diagnostics. We developed a pipeline incorporating data preprocessing, model inference, and preference-based evaluation, expanding an initial set of 500 clinical cases to $\mathbf{3,000}$ through controlled augmentation. Our method combined medical images with clinical observations to generate assessments, using Claude 3.5 Sonnet for independent evaluation against physician-authored diagnoses. The results indicated varying performance across models, with Llama 3.290B outperforming human diagnoses in 85.27% of cases. In contrast, specialized vision models like BLIP2 and Llava showed preferences in 41.36% and 46.77% of cases, respectively. This framework highlights the potential of large multimodal models to outperform human diagnostics in certain tasks.