Reasoning with minimal models has always been at the core of many knowledge representation techniques, but we still have only a limited understanding of this problem in Description Logics (DLs). Minimization of some selected predicates---letting the remaining predicates vary or be fixed, as proposed in circumscription---has been explored and exhibits high complexity. The case of `pure' minimal models, where the extension of all predicates must be minimal, has remained largely uncharted. We address this problem in popular DLs and obtain surprisingly negative results: concept satisfiability in minimal models is undecidable already for EL. This undecidability also extends to a very restricted fragment of tuple-generating dependencies. To regain decidability, we impose acyclicity conditions on the TBox that bring the worst-case complexity below double exponential time and allow us to establish a connection with the recently studied pointwise circumscription; we also derive results in data complexity. We conclude with a brief excursion to the DL-Lite family, where a positive result was known for DL-Lite_core, but our investigation establishes ExpSpace-hardness already for its extension DL-Lite_horn.