Machine learning in evolutionary studies comes of age

Whether flowers, mosquitoes, or humans, all organisms tend to interact and reproduce with others of their ilk who are close by. In principle, that means that their genetics can reveal not only their ancestry but also their geography. Taking advantage of this simple insight, evolutionary geneticists recently showed that it was possible to create models, based on scanning thousands of genomes from mosquitoes to elephants to humans (Fig. 1), that match individual genomes to spatial locations and therefore predict where a given individual animal was born (1, 2). The approach has practical import: It could be applied in the context of ecology and conservation by, for example, tracing the origins of elephant tusks and rare woods. It’s one of a variety of new machine learning methods that are finding applications in the field, shedding light on longstanding questions about the forces that shape genomes, such as selection and genetic drift. These approaches have already demonstrated the potential to deal with the messiness of real data in ways that formal population genetic theory cannot. In the early 2000s, researchers who were “thinking a little bit ahead,” says evolutionary geneticist Andrew A variety of new machine learning methods are shedding light on longstanding questions about the forces that shape genomes over time. Image credit: Shutterstock/ alionaprof.

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Machine learning in evolutionary studies comes of age

Semantic Scholar · Computer Science · 2022

Abstract

Whether flowers, mosquitoes, or humans, all organisms tend to interact and reproduce with others of their ilk who are close by. In principle, that means that their genetics can reveal not only their ancestry but also their geography. Taking advantage of this simple insight, evolutionary geneticists recently showed that it was possible to create models, based on scanning thousands of genomes from mosquitoes to elephants to humans (Fig. 1), that match individual genomes to spatial locations and therefore predict where a given individual animal was born (1, 2). The approach has practical import: It could be applied in the context of ecology and conservation by, for example, tracing the origins of elephant tusks and rare woods. It’s one of a variety of new machine learning methods that are finding applications in the field, shedding light on longstanding questions about the forces that shape genomes, such as selection and genetic drift. These approaches have already demonstrated the potential to deal with the messiness of real data in ways that formal population genetic theory cannot. In the early 2000s, researchers who were “thinking a little bit ahead,” says evolutionary geneticist Andrew A variety of new machine learning methods are shedding light on longstanding questions about the forces that shape genomes over time. Image credit: Shutterstock/ alionaprof.

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