Development and validation of deep learning models for bowel obstruction on plain abdominal radiograph

Abstract

Objective Artificial intelligence (AI) could help medical practitioners in analyzing radiological images to determine the presence and site of bowel obstruction. This retrospective diagnostic study proposed a series of deep learning (DL) models for diagnosing bowel obstruction on abdominal radiograph. Methods A total of 2082 upright plain abdominal radiographs were retrospectively collected from four hospitals. The images were labeled as normal, small bowel obstruction and large bowel obstruction by three senior radiologists based on comprehensive examinations and interventions within 48 hours after admission. Gradient-weighted class activation mapping was used to visualize the inferential explanation. Results In the validation set, the Xception-backboned model achieved the highest accuracy (0.863), surpassing the VGG16 (0.847) and ResNet models (0.836). In the test set, the Xception model (accuracy: 0.807) outperformed other models and a junior radiologist (0.780) but not a senior radiologist (0.840). In the AI-aided diagnostic framework, the junior and senior radiologists made their judgements while aware of the Xception model predictions. Their accuracy significantly improved to 0.887 and 0.913, respectively. Conclusions We developed and validated DL-based computer vision models for diagnosing bowel obstruction on plain abdominal radiograph. DL-based computer-aided diagnostic systems could reduce medical practitioners’ workloads and improve diagnostic accuracy.