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Statistical Methods in Clinical Trials

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001Automatic prediction of patients early discontinuation in oncology clinical trialsOpenAlexPaperL. Olgiati, Quentin Filori et al.Jul 23
002Estimating confidence interval of difference in optimal accuracy achieved by overlapping (or nested) groups of clinical biomarkers under multivariate normalityOpenAlexPaperNan Nan, Lili TianJul 16
003DPΦ Order-Geometry Toy Model: Preregistration of a DPT-Native Geometry Selection TestOpenAlexPaperDebra S. GavantJul 14
004Evaluating Missing Data Imputation Strategies for Environmental Mixture Models: A Simulation Study and Applied AnalysisOpenAlexPaperYvonne S. Boafo, Sayed Mostafa et al.Jul 14
005AI-Driven Clinical Operations as an Example of URM in Drug Trials: Operational AI, Dynamic Trial Instability, and the Universal Resonance ModelOpenAlexPaperAnita DomargårdJul 3
006AI-Driven Clinical Operations as an Example of URM in Drug Trials: Operational AI, Dynamic Trial Instability, and the Universal Resonance ModelOpenAlexPaperAnita DomargårdJul 3
007Amendment008OpenAlexPaperGlen J. WeissJul 1
008Beta-trees for testing multivariate goodness-of-fit and localizing deviations from a modelOpenAlexPaperValerie N. P. Ho, Guenther WaltherJun 27
009<p>Minimal dataset containing individual clinicopathological and immunohistochemical data used for statistical analyses.</p>OpenAlexPaperYoshiaki Zaizen, Takuma Koga (23117893) et al.Jun 8
010Artificial Intelligence in Clinical Trials Development: A Systematic Approach and OverviewOpenAlexPaperYash Surti*1, Atharva Ambekar2, Harsh More3, Samali Raut4Jun 3
011Artificial Intelligence in Clinical Trials Development: A Systematic Approach and OverviewOpenAlexPaperYash Surti*1, Atharva Ambekar2, Harsh More3, Samali Raut4Jun 3
012Evaluating a multiplex diagnostic test using partially ordered Bayes classifierOpenAlexPaperYing Kuen Cheung, Louise KuhnJun 1
013Predicting progression-free and overall survival from response endpoints in oncology clinical trials: An embedding-based machine learning approach.OpenAlexPaperAnkit Kalucha, Judith Pérez‐Granado et al.May 28
014Selective randomization inference for adaptive experimentsOpenAlexPaperTobias Freidling, Qingyuan Zhao et al.May 27
015Regulatory Considerations for Using Artificial Intelligence Models to Reduce Sample Sizes in Registrational StudiesOpenAlexPaperAaron M. Smith, Tala Fakhouri et al.May 22
016AI-simulated placebo arms in clinical trials: efficiency should not outpace methodological rigorOpenAlexPaperSami Ullah, Muhammad Abdullah Gulzar et al.May 20
017Prediction-powered inference in clinical trials with survival outcomesOpenAlexPaperMaylis Tran, Pierre-Emmanuel Poulet et al.May 15
018Robust and Data-Adaptive Integration of Nonconcurrent Data in Platform Trials via Gaussian ProcessesOpenAlexPaperYuhan Qian, Yu Du et al.May 14
019Bayesian Precision Medicine.OpenAlexPaperYang NiMay 13
020Testing Hypotheses Generated by ConstraintsOpenAlexPaperMartin Larsson, Aaditya Ramdas et al.May 12
021TUTORIAL - Multiple Clinical Trial Designs for AIOpenAlexPaperMajid AfsharMay 8
022TUTORIAL - Multiple Clinical Trial Designs for AIOpenAlexPaperMajid AfsharMay 8
023TUTORIAL - Multiple Clinical Trial Designs for AIOpenAlexPaperMajid Afshar, Mary Beth Hamel et al.May 8
024Complexity metrics for Tomotherapy: application to the verification of transferred plansOpenAlexPaperL. Simon, J. Seguret et al.May 1
025Machine Learning in Personalized Medication Regimen Design for the Geriatric Population: Integrating Pharmacokinetic and Pharmacodynamic Modeling with Clinical Decision-MakingOpenAlexPaperAhmad R. Alsayed, Mohanad Al-Darraji et al.Apr 21
026Likelihood inference for semiparametric mixture cure generalized-gamma frailty modelOpenAlexPaperMu He, Kai Liu et al.Apr 19
027Confidence envelopes for the false discoveries with heterogeneous dataOpenAlexPaperRomain Périer, Gilles Blanchard et al.Apr 10
028A finite-sample augmented likelihood ratio test for mediationOpenAlexPaperKees Jan van Garderen, Noud P A van GiersbergenApr 9
029Improving Population Pharmacokinetic Modelling with Artificial Patients using Generative Artificial Intelligence.OpenAlexPaperVerena Schöning, Felix HammannApr 1
030Modeling of Aggregate Losses of Metastatic Cancer Using Katz Family (a, b, 0) DistributionsOpenAlexPaperCynthia M. Mwau, Omukami HowardApr 1
031Testing hypotheses generated by constraintOpenAlexPaperMartin Larsson, Aaditya Ramdas et al.Mar 22
032Adaption: 21 CFR Part 312, End-to-End Physical AI Oncology Clinical Trial UnificationOpenAlexPaperKevin KawchakMar 17
033Adaption: 21 CFR Part 312, End-to-End Physical AI Oncology Clinical Trial UnificationOpenAlexPaperKevin KawchakMar 17
034Applications of Bayesian Statistics in MedicineOpenAlexPaperXiangyu ZhaMar 16
035Enhancing Data Quality in Clinical Trials: Cross-Company Validation of the Open-Source Clinical Trial Anomaly Spotter (CTAS)OpenAlexPaperPekka Tiikkainen, Frederik Collin et al.Mar 12
036Leveraging generative AI to transform statistical analysis plan authoring in clinical trialsOpenAlexPaperRogier Landman, B. Emir et al.Mar 3
037Predicting Clinical Trial Site Performance using Machine LearningOpenAlexPaperSumanth SinghFeb 12
038Maximum Binomial Likelihood Method for Multivariate Mixture DataOpenAlexPaperTao Yu, Jing Qin et al.Feb 9
039Symmetric <i>α</i> -stable distribution for robust semiparametric mixture of regression modelsOpenAlexPaperShaho ZareiFeb 4
040Advances and trends in technology and application of virtual clinical trialsOpenAlexPaperChen-Qi JIN, Jing MENG et al.Feb 1
041FlexReg: an R package for fitting a general class of mixture regression models with bounded responses in a Bayesian frameworkOpenAlexPaperRoberto Ascari, Agnese Maria Di Brisco et al.Feb 1
042An improved density approximation for the Zivot–Andrews testOpenAlexPaperRiccardo LucchettiJan 27
043On the Number of Replications in Resampling Tests and Monte Carlo Simulation StudiesOpenAlexPaperDaniel Gaigall, Julian GerstenbergJan 8
044On the number of replications in resampling tests and Monte Carlo simulation studiesOpenAlexPaperDaniel Gaigall, Julian GerstenbergJan 8
045Asymptotic distribution of the likelihood ratio test statistic with inequality-constrained nuisance parametersOpenAlexPaperClara Bertinelli SalucciJan 7
046Principles and Procedures for Generating Non-Normal Data Using Mixture ModelsOpenAlexPaperKyungmin Lim, Minjoo Kim et al.Jan 5
047A Dirichlet‐Multinomial Gibbs Algorithm for Assessing the Accuracy of Binary Tests in the Absence of a Gold StandardOpenAlexPaperJoseph B. KadaneJan 1
048Bayesian Evidence Synthesis under HeterogeneityOpenAlexPaperBjörn Alfons EdmarJan 1
049How <scp>AI</scp> Transforms Regulatory Submission: Current Clinical Implementation and Future ProspectsOpenAlexPaperJagdeep T. Podichetty, Anna‐Marika Bauer et al.Dec 1, 2025
050Tolerance Intervals Using Dirichlet ProcessesOpenAlexPaperSeokjun Choi, Tony Pourmohamad et al.Dec 1, 2025
051Comparative Analysis of Transformer-Based Embedding Models for Clinical Trial RetrievalOpenAlexPaperSarthak Srivastava, Arti Devi et al.Nov 17, 2025
052Predictive <scp>AI</scp> in Clinical Pharmacology: A Call to Action to Develop Robust Benchmarking PracticesOpenAlexPaperAna Victoria Ponce Bobadilla, Dominic Stefan Bräm et al.Nov 13, 2025
053Signature Maximum Mean Discrepancy Two-Sample Statistical TestsOpenAlexPaperAndrew Alden, Blanka Horvath et al.Nov 7, 2025
054Mixture model formula and additional model statistics.OpenAlexPaperEvgeny Chukharev (22552627), Jens Roeser (22383980) et al.Nov 3, 2025
055Using mixture cure models to address algorithmic bias in diagnostic timing: autism as a test caseOpenAlexPaperPeng Wu, Naomi Davis et al.Nov 3, 2025
056Pattern-Mixture Models for Missing DataOpenAlexPaperRoderick J. A. LittleOct 30, 2025
057Statistical interpretation of cases involving mixtures: A Spanish and Portuguese-Speaking Working Group (GHEP-ISFG) collaborative exerciseOpenAlexPaperCamila Costa, Juan Carlos Álvarez et al.Oct 28, 2025
058Value of diversity characteristics in predictive modeling: ACS screening as a case studyOpenAlexPaperGabrielle Bunney, Kate Miller et al.Oct 21, 2025
059TrialPred: an interpretability model based on multimodal data for predicting the duration of clinical trialsOpenAlexPaperTianxing Zhou, J. Huang et al.Oct 12, 2025
060A Comparison of <scp>AI</scp> and Population <scp>PK</scp> Models to Predict the Concentrations of Antiepileptic Drugs Using Therapeutic Drug Monitoring RecordsOpenAlexPaperTae Kyu Chung, Howard LeeOct 1, 2025

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