METHOD FOR DIAGNOSING CANCER AND PREDICTING CANCER TYPE BY USING TERMINAL SEQUENCE MOTIF FREQUENCY AND SIZE OF CELL-FREE NUCLEIC ACID FRAGMENT

Patent №

US 12,374,462

Granted

2025-07-29

Filed 2023

Owner

GC GENOME CORPORATION

Lab

AI components

0

Assignment

None on record

Dataset

AIPD

Application

18171360

Disclosed is a method for diagnosing cancer and predicting a cancer type using fragment end motif frequencies and sizes of cell-free nucleic acid, and more preferably, to a method for diagnosing cancer and predicting a cancer type by extracting nucleic acids from a biological sample to obtain sequence information, acquiring fragment end motif frequencies and sizes of nucleic acids based on the aligned reads, converting the fragment end motif frequencies and sizes of nucleic acids into vectorized data, inputting the vectorized data to a trained artificial intelligence model and analyzing a resulting calculated value. The method includes generating vectorized data and analyzing the same using an AI algorithm and thus is useful due to high sensitivity and accuracy thereof even in the case of low read coverage.

G16H 50/20G16H 50/50G16H 10/40G16H 30/20G16H 50/70G16H 30/40G16B 30/10G16B 40/00+12 more

Ownership

GC GENOME CORPORATION

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