CT-FREE ATTENUATION CORRECTION FOR SPECT USING DEEP LEARNING WITH IMAGING AND NON-IMAGING INFORMATION

A system based upon artificial neural networks generates attenuation-corrected SPECT from non-attenuation-corrected SPECT (single photon emission computed tomography) without or with an intermediate step of attenuation map estimation. The system includes a SPECT scanner with CZT cameras for dynamic SPECT imaging. The system also includes a machine learning system including a 3D Dual Squeeze-and-Excitation Residual Dense Network for generating attenuation-corrected SPECT or attenuation maps from non-attenuation-corrected SPECT. The machine learning system reconstructs images from photopeak window and one or more scatter windows of the SPECT scanner are fed to the 3D Dual Squeeze-and-Excitation Residual Dense Network to generate attenuation-corrected SPECT or attenuation maps.