Patent US 4,172,835

1-(Phenylamino)pyrrole, useful as a urinary antiseptic, hypotensive and hypoglycemic agent, is prepared by reaction of an N-benzoylphenylhydrazine or N-lower-alkanoylphenylhydrazine or a lower-alkanealdehyde N-benzoylphenylhydrazone or N-lower-alkanoylphenylhydrazone with a 2,5-di-lower-alkoxytetrahydrofuran followed by hydrolytic removal of the benzoyl or lower-alkanoyl group from the resulting N-benzoyl-1-(phenylamino)pyrrole or N-lower-alkanoyl-1-(phenylamino)pyrrole.