SAMPLE INTRODUCTION SYSTEM FOR INDUCTIVELY COUPLED PLASMA AND OTHER GAS-PHASE, OR PARTICLE, DETECTORS UTILIZING ULTRASONIC NEBULIZATION, AND METHOD OF USE.

An efficient sample introduction system and method of use, for accepting liquid sample solutions, nebulizing them to form nebulized sample solution droplets, and introducing the nebulized sample solution droplets to sample analysis systems is disclosed. In the preferred embodiment desolvation of produced nebulized sample solution droplets, and solvent removal, to provide nebulized sample particles is performed prior to entering sample to a sample analysis system. Nebulization of sample solutions is accomplished by use of high efficiency ultrasonic nebulizers and solvent removal is accomplished by use of high efficiency enclosed filter and solvent vapor removal gas flow or low temperature condenser systems. The sample introduction system provides improved sample solution nebulization, desolvation and solvent removal, as well as reduced sample loss and carry-over of sample from one analysis procedure to a subsequent analysis procedure, as compared to other systems which perform a similar overall function. The sample introduction system also enhances transport of sample through the sample introduction system to a sample analysis system. The present invention is equally effective with sample solutions in which the sample solvent is either water, or an organic solvent. The preferred embodiment of the present invention also teaches air cooling of the vibrational energy producing elements; and vibrational energy directing and focusing element which serves to increase the operational efficiency and lifetime of the ultrasonic nebulizer.