APPARATUS AND METHOD FOR AUTOMATED PROTEIN DESIGN

Patent №

US 6,188,965

Granted

2001-02-13

Filed 1998

Owner

CALIFORNIA INSTITUTE OF TECHNOLOGY

Lab

—

AI components

ml · evo · hardware

Assignment

Recorded

Dataset

AIPD

2023_r1 edition

Application

09058459

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The present invention relates to apparatus and methods for quantitative protein design and optimization.

Machine learning Evolutionary computation AI hardwareC12N 15/1089C07K 1/00C07K 1/003C07K 14/001C12N 15/1034G16B 15/00G16B 15/20G16B 20/50+2 more

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AI classification

Evolutionary computation1.00

Machine learning1.00

AI hardware0.85

Knowledge representation0.44

Planning0.08

Natural language0.03

Speech0.00

Vision0.00

Ownership

CALIFORNIA INSTITUTE OF TECHNOLOGY

assignment · 108930095

Assignors

MAYO, STEPHEN L., DAHIYAT, BASSIL I., GORDON, D. BENJAMIN, STREET, ARTHUR

On an employer assignment, the assignors are typically the inventors.

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Cited by (43)

Polypeptides Capable of Forming Homo-Oligomers with Modular Hydrogen Bond Network-Mediated Specificity and Their DesignUS 10,988,514 · 2021 SYSTEM AND METHOD FOR DETERMINING CONTINGENT RELEVANCEUS 10,943,273 · 2021 QUALITATIVE AND QUANTITATIVE MASS SPECTRAL ANALYSISUS 10,755,905 · 2020 METHOD AND APPARATUS FOR IDENTIFICATION OF BIOMOLECULESUS 10,223,499 · 2019 AGENT TRAINING SENSITIVE CALL ROUTING SYSTEMUS 8,971,519 · 2015 ESTIMATION OF PROTEIN-COMPOUND INTERACTION AND RATIONAL DESIGN OF COMPOUND LIBRARY BASED ON CHEMICAL GENOMIC INFORMATIONUS 8,949,157 · 2015 METHOD FOR GENERATING INFORMATION RELATED TO THE MOLECULAR STRUCTURE OF A BIOMOLECULEUS 8,571,806 · 2013 METHODS OF POPULATING DATA STRUCTURES FOR USE IN EVOLUTIONARY SIMULATIONSUS 8,170,806 · 2012 METHODS FOR IDENTIFYING AND PRODUCING POLYPEPTIDESUS 7,957,912 · 2011 METHODS FOR IDENTIFYING SETS OF OLIGONUCLEOTIDES FOR USE IN AN IN VITRO RECOMBINATION PROCEDURESUS 7,904,249 · 2011 METHODS AND APPARATUS FOR PREPARING HIGH-DIMENSIONAL COMBINATORIAL EXPERIMENTSUS 7,882,053 · 2011 METHOD AND SYSTEM USING SYSTEMATICALLY VARIED DATA LIBRARIESUS 7,873,477 · 2011 METHODS OF POPULATING DATA STRUCTURES FOR USE IN EVOLUTIONARY SIMULATIONSUS 7,873,499 · 2011 METHODS FOR MAKING POLYNUCLEOTIDES HAVING DESIRED CHARACTERISTICSUS 7,853,410 · 2010 METHODS AND SYSTEMS FOR GENERATING AND EVALUATING PEPTIDESUS 7,739,055 · 2010 METHOD AND APPARATUS FOR CODON DETERMININGUS 7,702,464 · 2010 METHODS OF GENERATING VARIANT ANTIBODIES WITH INCREASED HOST STRING CONTENTUS 7,657,380 · 2010 METHODS FOR IDENTIFYING SETS OF OLIGONUCLEOTIDES FOR USE IN AN IN VITRO RECOMBINATION PROCEDUREUS 7,620,502 · 2009 METHODS FOR RATIONAL PEGYLATION OF PROTEINSUS 7,610,156 · 2009 METHODS AND SYSTEMS FOR GENERATING PEPTIDESUS 7,603,239 · 2009 METHODS FOR RATIONAL PEGYLATION OF PROTEINSUS 7,587,286 · 2009 METHODS OF POPULATING DATA STRUCTURES FOR USE IN EVOLUTIONARY SIMULATIONSUS 7,430,477 · 2008 IDENTIFYING OLIGONUCLEOTIDES FOR IN VITRO RECOMBINATIONUS 7,421,347 · 2008 PROTEIN DESIGN AUTOMATION FOR PROTEIN LIBRARIESUS 7,315,786 · 2008 APPARATUS AND METHOD FOR DESIGNING PROTEINS AND PROTEIN LIBRARIESUS 7,231,328 · 2007

and 18 more

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