NUCLEAR RECEPTOR LIGANDS AND LIGAND BINDING DOMAINS

Patent №

US 6,236,946

Granted

2001-05-22

Filed 1996

Owner

REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE

Lab

Berkeley AI Research (BAIR)

AI components

Assignment

Recorded

Dataset

AIPD

2023_r1 edition

Application

08764870

The present invention provides new methods, particularly computational methods, and compositions for the generation of nuclear receptor synthetic ligands based on the three dimensional structure of nuclear receptors, particularly the thyroid receptor (herein referred to as "TR"). Also provided are crystals, nuclear receptor synthetic ligands, and related methods.

Machine learningC07K 14/72A61P 3/00A61P 3/06A61P 5/00A61P 5/14C07K 2299/00

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Ownership

REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE

assignment · 84290722

Assignors

SCANLAN, THOMAS S., BAXTER, JOHN D., FLETTERICK, ROBERT J., WAGNER, RICHARD L., KUSHNER, PETER J., APRILETTI, JAMES W., WEST, BRIAN L., SHIAU, ANDREW K.

On an employer assignment, the assignors are typically the inventors.

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