SYSTEM AND METHOD FOR SYNTHESIZING LEADS OF AN ELECTROCARDIOGRAM

A method for synthesizing electrocardiogram leads includes obtaining a sequence of voltage-time measurements for a set of electrocardiogram leads and subjecting the measurements to abstract factor analysis to obtain a set of eigenvalues and associated eigenvectors. A minimal subset of electrocardiogram leads is identified from which the voltage-time measurements can be calculated with acceptable error. Simplex optimization is performed on a subset of the voltage-time measurements measured with the minimal subset of electrocardiogram leads to obtain a universal transformation matrix, and the universal transformation matrix is multiplied by the subset of the voltage-time measurements to calculate the full set of voltage-time measurements. The full set of leads can be used to calculate a body surface map, and the eigenvalues can be tracked in time to predict the onset of pathology such as myocardial infarction.