IMAGE-BASED METHODS FOR MEASURING GLOBAL NUCLEAR PATTERNS AS EPIGENETIC MARKERS OF CELL DIFFERENTIATION

Patent №

US 7,907,769

Granted

2011-03-15

Filed 2009

Owner

THE CHARLES STARK DRAPER LABORATORY, INC.

+1 more

Lab

—

AI components

vision · hardware

Assignment

Recorded

Dataset

AIPD

2023_r1 edition

Application

12321360

The invention provides methods for determining the differentiation state of cells. The methods include non-invasive, non-perturbing, automatable, and quantitative methods of analysis of cell colonies, individual cells, and/or cellular structures.

Vision AI hardwareG06T 7/0014G06F 18/2411G06T 7/42G06V 10/764G06V 20/69G06T 2207/10056G06T 2207/20064G06T 2207/30024

Google Patents

AI classification

Vision0.99

AI hardware0.74

Planning0.02

Machine learning0.01

Natural language0.00

Evolutionary computation0.00

Speech0.00

Knowledge representation0.00

Ownership

THE CHARLES STARK DRAPER LABORATORY, INC.

assignment · 257330361

UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION

assignment · 257330443

Assignors

MANGOUBI, RAMI

On an employer assignment, the assignors are typically the inventors.

From the same owner

Apparatus for High Density Information Storage in Molecular ChainsUS 11,995,558 · 2024 Robot Interaction With Human Co-WorkersUS 11,872,702 · 2024 Metadata Programmable TagsUS 11,782,714 · 2023 Multi-Source Distributed Navigation System ArchitectureUS 11,774,602 · 2023 CO-ADAPTATION FOR LEARNING AND CONTROL OF DEVICESUS 11,755,902 · 2023 Techniques For Metadata ProcessingUS 11,720,361 · 2023 Systems and Methods for Policy Execution ProcessingUS 11,709,680 · 2023 Food-Safe, Washable, Thermally-Conductive Robot CoverUS 11,673,268 · 2023

Cites (21)

COMPUTER-AIDED IMAGE ANALYSISUS 7,383,237 · 2008 METHOD AND APPARATUS FOR LOW DEPTH OF FIELD IMAGE SEGMENTATIONUS 7,302,096 · 2007 APPARATUS AND METHODS FOR BRAIN RHYTHM ANALYSISUS 7,299,088 · 2007 IMAGING SYSTEM AND METHODOLOGYUS 7,151,246 · 2006 ANIMAL CAGE BEHAVIOR SYSTEMUS 7,086,350 · 2006 REGION EXTRACTION IN VECTOR IMAGESUS 7,088,845 · 2006 METHODS TO INCREASE THE CAPACITY OF HIGH CONTENT CELL-BASED SCREENING ASSAYSUS 7,085,765 · 2006 TECHNIQUE FOR MANIPULATING MEDICAL IMAGESUS 6,799,066 · 2004 METHOD FOR ANALYZING DETECTIONS IN A SET OF DIGITAL IMAGES USING CASE BASED NORMALCY CLASSIFICATIONUS 6,763,128 · 2004 DEFECT DETECTION SYSTEM FOR QUALITY ASSURANCE USING AUTOMATED VISUAL INSPECTIONUS 6,753,965 · 2004 SYSTEM FOR CELL-BASED SCREENINGUS 6,727,071 · 2004 RAY-BASED IMAGE ANALYSIS FOR BIOLOGICAL SPECIMENSUS 6,658,143 · 2003 AUTOMATED SEGMENTATION METHOD FOR 3-DIMENSIONAL ULTRASOUNDUS 6,385,332 · 2002 METHOD AND APPARATUS USING BAYESIAN SUBFAMILY IDENTIFICATION FOR SEQUENCE ANALYSISUS 6,128,587 · 2000 SYSTEM FOR CELL-BASED SCREENINGUS 5,989,835 · 1999 AUTOMATED METHOD AND SYSTEM FOR IMAGE SEGMENTATION IN DIGITAL RADIOGRAPHIC IMAGESUS 5,825,909 · 1998 AUTOMATED METHOD AND SYSTEM FOR REGION DECOMPOSITION IN DIGITAL RADIOGRAPHIC IMAGESUS 5,757,953 · 1998 METHOD AND APPARATUS FOR AUTOMATED ANALYSIS OF BIOLOGICAL SPECIMENSUS 5,526,258 · 1996 SYSTEM FOR SHAPE RECOGNITIONUS 4,905,296 · 1990 Patent US 4,150,360US 4,150,360 Patent US 6,167,146US 6,167,146

Cited by (58)

ASSESSING HEALTH RISKS USING GENETIC, EPIGENETIC, AND PHENOTYPIC DATA SOURCESUS 11,705,230 · 2023 APPROACH FOR AFTERTREATMENT SYSTEM MODELING AND MODEL IDENTIFICATIONUS 11,687,688 · 2023 DEVICES, SYSTEMS, AND METHODS FOR FLUORESCENCE LIFETIME IMAGING MICROSCOPYUS 11,579,084 · 2023 AUTOMATED EVALUATION OF HUMAN EMBRYOSUS 11,321,831 · 2022 SYSTEM AND METHOD FOR CLASSIFYING CELLS IN TISSUE IMAGES BASED ON MEMBRANE FEATURES

Related research

Machine Learning for Nuclear Mechano-Morphometric Biomarkers in Cancer DiagnosisSemantic Scholar Estimation of Three-Dimensional Chromatin Morphology for Nuclear Classification and CharacterisationOpenAlex A deep learning method that identifies cellular heterogeneity using nanoscale nuclear featuresSemantic Scholar A machine learning approach for single cell interphase cell cycle stagingSemantic Scholar Machine learning approach for discrimination of genotypes based on bright-field cellular imagesSemantic Scholar

Full text

Google Patents