COMBINED SEGMENTATION AND REGISTRATION FRAMEWORK FOR PARAMETRIC SHAPES

Progress monitoring of lesions is done automatically by segmentation and registration of lesions in multi-phase medical images. A parametric level-set framework includes a model optimization for any number of lesions. The user specifies lesions in a baseline volume by clicking inside of them. The apparatus segments the lesions automatically in the baseline and follow-up volumes. The segmentation optimization compensates for lesion motion between baseline and follow-up volumes. 2D and 3D medical patient data can be processed by the methods.