METHOD OF ANALYZING CELL OR THE LIKE HAVING LINEAR SHAPE, METHOD OF ANALYZING NERVE CELL AND APPARATUS AND PROGRAM FOR PERFORMING THESE METHODS
Patent №
US 8,077,945
Granted
2011-12-13
Filed 2008
Owner
UNIVERSITY OF TOKYO, THE
Lab
—
AI components
2
vision · hardware
Assignment
Recorded
Dataset
AIPD
2023_r1 edition
Application
12086496
It is intended to propose a technique whereby a nerve cell is morphologically analyzed automatically based on a three-dimensional image of the nerve cell. First, a dendritic projection is traced by using the scale space method. In this step, irregularities are reduced by using the σ-convolution smoothing method and thus the center line of the dendritic projection is identified. Next, a negative curvature is searched for by the Hess tensor method. The part corresponding to the negative curvature in all coordinate axes is judged as the area occupied by “heads”. The center of this area (heads) is referred to as the spine position. Approximation is made on the assumption that the spine head has an ellipsoidal shape. Thus, the minor diameter, medium diameter and major diameter of the ellipsoid are calculated. From the spine position, a perpendicular line is dropped toward the dendritic projection closest thereto and this perpendicular line is considered as the column part. By combining the dendritic projection with the spine head and column thus obtained, the final morphological shape of the nerve cell is obtained.
AI classification
Ownership
UNIVERSITY OF TOKYO, THE
assignment · 213930603
Assignors
KAWATO, SUGURU, MITSUHASHI, KENJI
On an employer assignment, the assignors are typically the inventors.