METHODS AND COMPOSITIONS FOR MODIFICATION OF A HLA LOCUS

Patent №

US 8,945,868

Granted

2015-02-03

Filed 2011

Owner

BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEMS

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AI components

planning

Assignment

Recorded

Dataset

AIPD

2023_r1 edition

Application

13188417

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Disclosed herein are methods and compositions for modulating the expression of a HLA locus or for selectively deleting or manipulating a HLA locus or HLA regulator.

PlanningC07K 14/70539A61K 40/11A61K 40/31A61K 40/4211A61P 3/00A61P 5/14A61P 5/38A61P 7/02+13 more

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Ownership

BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEMS

assignment · 272550598

SANGAMO BIOSCIENCES, INC.

assignment · 272550603

SANGAMO THERAPEUTICS, INC.

namechg · 463960408

Assignors

COLLINGWOOD, TREVOR, GREGORY, PHILIP D., HOLMES, MICHAEL C., MILLER, JEFFREY C., REBAR, EDWARD J., REIK, ANDREAS, URNOV, FYODOR

On an employer assignment, the assignors are typically the inventors.

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Cites (16)

POSITION DEPENDENT RECOGNITION OF GNN NUCLEOTIDE TRIPLETS BY ZINC FINGERSUS 7,030,215 · 2006 REGULATION OF ENDOGENOUS GENE EXPRESSION IN CELLS USING ZINC FINGER PROTEINSUS 7,013,219 · 2006 MODULATION OF ENDOGENOUS GENE EXPRESSION IN CELLSUS 6,933,113 · 2005 ITERATIVE OPTIMIZATION IN THE DESIGN OF BINDING PROTEINSUS 6,794,136 · 2004 CELLS FOR DRUG DISCOVERYUS 6,689,558 · 2004 REGULATION OF ENDOGENOUS GENE EXPRESSION IN CELLS USING ZINC FINGER PROTEINSUS 6,607,882 · 2003 REGULATION OF ENDOGENOUS GENE EXPRESSION IN CELLS USING ZINC FINGER PROTEINSUS 6,534,261 · 2003 METHODS OF USING RANDOMIZED LIBRARIES OF ZINC FINGER PROTEINS FOR THE IDENTIFICATION OF GENE FUNCTIONUS 6,503,717 · 2003 POLY ZINC FINGER PROTEINS WITH IMPROVED LINKERSUS 6,479,626 · 2002 GENERAL STRATEGY FOR SELECTING HIGH-AFFINITY ZINC FINGER PROTEINS FOR DIVERSE DNA TARGET SITESUS 6,410,248 · 2002 ZINC FINGER BINDING DOMAINS FOR GNNUS 6,140,081 · 2000 INTRACTION TRAP ASSAY, REAGENTS AND USES THEREOFUS 5,925,523 · 1999 Patent US 6,824,978US 6,824,978 Patent US 6,979,539US 6,979,539 Patent US 7,153,949US 7,153,949 Patent US 7,163,824US 7,163,824

Cited by (5)

GENETIC MODIFICATION OF CYTOKINE INDUCIBLE SH2-CONTAINING PROTEIN (CISH) GENEUS 11,661,611 · 2023 LIVER-SPECIFIC CONSTRUCTS, FACTOR VIII EXPRESSION CASSETTES AND METHODS OF USE THEREOFUS 11,452,782 · 2022 TARGETED DISRUPTION OF THE T CELL RECEPTORUS 11,352,631 · 2022 HTT REPRESSORS AND USES THEREOFUS 10,435,441 · 2019 Patent US 11,123,443

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