The rapid increase in multimodal data availability has sparked significant interest in cross-modal knowledge distillation (KD) techniques, where richer"teacher"modalities transfer information to weaker"student"modalities during model training to improve performance. However, despite successes across various applications, cross-modal KD does not always result in improved outcomes, primarily due to a limited theoretical understanding that could inform practice. To address this gap, we introduce the Cross-modal Complementarity Hypothesis (CCH): we propose that cross-modal KD is effective when the mutual information between teacher and student representations exceeds the mutual information between the student representation and the labels. We theoretically validate the CCH in a joint Gaussian model and further confirm it empirically across diverse multimodal datasets, including image, text, video, audio, and cancer-related omics data. Our study establishes a novel theoretical framework for understanding cross-modal KD and offers practical guidelines based on the CCH criterion to select optimal teacher modalities for improving the performance of weaker modalities.
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