EFFICIENT CIS-ELEMENT DISCOVERY METHOD USING MULTIPLE SEQUENCE COMPARISONS BASED ON EVOLUTIONARY RELATIONSHIPS
Patent №
US 6,917,883
Granted
2005-07-12
Filed 2003
Owner
YALE UNIVERSITY
Lab
—
AI components
2
ml · evo
Assignment
Recorded
Dataset
AIPD
2023_r1 edition
Application
10345080
A method is described for efficiently searching non-coding DNA for known control elements. Short conserved DNA sequences can be identified among 3 or more species by selecting DNA sequences from species having a total genetic distance larger than one substitution per site at a neutrally evolving region and calculating the total substitutions using pair-wise genetic distances, with the pairs for comparison selected based on phylogenetic relationships.
AI classification
Ownership
YALE UNIVERSITY
assignment · 136480184
Assignors
RUDDLE, FRANK H., SUMIYAMA, KENTA, KIM, CHANG-BAE
On an employer assignment, the assignors are typically the inventors.