Metric temporal logic (MTL) provides a formal framework for defining time-dependent mission requirements on autonomous vehicles. However, optimizing control decisions subject to these constraints is often computationally expensive. This article presents a method that uses reachability analysis to implicitly express the set of states satisfying an MTL specification and then optimizes to find a motion plan. The hybrid zonotope set representation is used to efficiently and conveniently encode MTL specifications into reachable sets. A numerical benchmark highlights the proposed method's computational advantages as compared to existing methods in the literature. Further numerical examples and an experimental application demonstrate the ability to address time-varying environments, region-dependent disturbances, and multi-agent coordination.